Writer Problems: Not Trusting yourself

I will admit it, I don't trust myself at all.  Especially when it comes to project I've been trying to query. 

Just when I think it's perfect, it gets rejected-- that's cool.  Believe me this post isn't about rejection, it's about confusion.

Here's teh thing, every time it's rejected, it's for totally different reasons.  So every time I'm rejected I look at the feedback, read through it, mull it over in my brain and think, "yep that sounds about right."
Then I fix the problem... I send it off to again to a different agent and BOOM I'm rejected again for a TOTALLY DIFFERENT REASON.

I've done so many tweeks and changes, that I can't figure out what's right and what's wrong. 

And here's the thing, I totally 100% thankful EVERY piece of feedback I've gotten.  My feedback has been WONDERFUL.  It's just it's all different.  It feels like I'm getting shut at by an machine gun and not a sniper rifle. 

So now I don't trust myself.  I don't know which way is up.  I only know this--- At it's core... I've got an AWESOME book, it's just the details I keep screwing up.

At this point I know perfection is out of my reach...but trying should be.

I have no solutions to this problem.

Maybe walking away for a little while and coming back to it is something.  And the advice trusting yourself is easier said than done.

What about you? Does anyone else have this problem?